Dini Lab Research
As part of the UC Davis School of Veterinary Medicine, we examine the fundamental and applied biology of sperm, eggs, embryos, and the biology of the equine placenta. Our primary research focuses on models encompassing Gamete Biology and Assisted Reproductive Technology (ART) in the following areas:
- Equine Assisted Reproduction Technology and in vitro production of horse embryos
- Embryo development and morphokinetics
- Equine placental development using organoids
- Placental pathologies in horses
- Oocyte maturation conditions
Conventional IVF with frozen-thawed sperm in Horses
Our lab marked a milestone in equine assisted reproductive technologies with the first successful use of frozen-thawed sperm for in vitro fertilization (IVF) production of equine embryos. Read more:
Manuscript:
https://doi.org/10.1016/j.theriogenology.2024.10.032
News:
https://x.com/AVMAvets/status/1856396934337962298
https://www.dvm360.com/view/uc-davis-achieves-first-equine-ivf-with-frozen-sperm
https://www.horseandhound.co.uk/news/equine-ivf-breakthrough-frozen-semen-878785
ICSI and Live Embryo Monitoring
Our laboratory is one of the few Assisted Reproductive Technology (ART) centers in the world equipped with live embryo monitoring system. Using an advanced imaging technology, MiriTL®, we can evaluate the development and precise formation of an embryo in real time.
Pulsation of an in vivo-produced embryo.https://doi.org/10.1016/j.jevs.2023.104891
Veterinary Assisted Reproduction Laboratory Support Fund
Click to support the Veterinary Assisted Reproduction Laboratory Support Fund
